A Novel Approach to Sequence Analysis using Assign-SBTTM Software Improves Heterozygous Base Calling: Implications for Re-sequencing, SNP detection and SNP scoring
Microsoft
A Novel Approach to Sequence Analysis using Assign-SBTTM Software Improves Heterozygous Base Calling: Implications for Re-sequencing, SNP detection and SNP
Despite intensive research efforts directed toward improvement of nucleotide dye labelling technology and modification of the polymerase used for automated DNA sequencing, the peak heights seen in sequence electropherogram data still vary significantly between positions within a sequence. This is largely because polymerase enzymes incorporate ...
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