Spatial transcriptomics is transforming how scientists see biology—literally—by mapping gene activity in its original location inside tissues. From decoding tumor architecture to charting entire ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...

Microglia are pivotal players in the neuroinflammatory landscape of Alzheimer’s disease (AD). Accumulating evidence underscores their complex role in ...

Cancer tumorigenesis is fundamentally driven by the profound dysregulation of gene regulatory networks (GRNs) and complex epigenetic alterations. With the ...

Scientists have produced the first comprehensive map of olfactory receptors in the mouse nose, overturning the belief that they were randomly arranged. Using advanced single-cell sequencing and ...

Researchers demonstrate improved spatial mapping technology that enhances transcript detection, identifies key tumor cell ...

Spatial transcriptomics (ST) has revolutionized biomedical research by enabling scientists to measure gene expression while ...

Transcriptomic phenotyping offers mechanistic insight into adipocyte biology and metabolic disease. A signature of adipocyte ...

From left to right and top to bottom: the researchers from IN CSIC-UMH Joan Galcerán, Berta L. Sánchez-Laorden, Khalil Kass ...