Objective Heart failure (HF) is a major public health issue due to its high morbidity, mortality and healthcare burden. This ...

Conservation levels of gene expression abundance ratios are globally coordinated in cells, and cellular state changes under such biologically relevant stoichiometric constraints are readable as ...

Objectives In the USA, an estimated 40–50 million operations are performed annually, with high rates of adverse events. Since the 1980s, report cards have been used for outcome measures and to improve ...