Tandem repeats are segments of DNA in which short nucleotide motifs are repeated in contiguous blocks. These repeated sequences—particularly short tandem repeats (STRs) composed of 1–6 base pair ...

All mammals have basically the same set of genes, yet there are obviously some significant differences that distinguish the various species. Recent research suggests that one such difference involves ...

Tandem repeats are hard to assess but important regions on the human genome. There are around 200 pathogenic and phenotypic tandem repeats, which are often ignored by standard analysis. Furthermore, ...

Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that could help explain why people experience disease differently, and why some ...

Tandem repeats of sequences in developmental genes may contribute to morphological evolution, according to a paper in this week's PNAS. John W. Fondon, III, and Harold R. Garner of the University of ...

Researchers have built the first genetic reference map for tandem repeat expansions, a critical tool for congenital disease research. Researchers at the University of California, Irvine (CA, USA) have ...

A research team has built a genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis ...

MENLO PARK, Calif., Sept. 27, 2022 /PRNewswire/ -- PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the availability of a new ...

Expanded repetitive sequences are infamous for causing inherited disease. Think poly-Q tracts that cause Huntington’s or the C9orf72 hexanucleotide run-ons that trigger ALS/FTD. However, given people ...

MENLO PARK, Calif., March 12, 2024 /PRNewswire/ -- PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today announced the PureTarget repeat expansion ...