Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Researchers increasingly turn to single-cell sequencing to answer a range of biological questions, with published single-cell data increasing year over year. As its popularity rises, so does the need ...

Researchers from the University of Adelaide, the National Center for Genomic Analysis, and St. Jude Children’s Research Hospital have developed a single-cell RNA analysis method that is 47 times more ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

(MEMPHIS, Tenn. – June 17, 2025) Single-cell RNA sequencing provides scientists with important information about gene expression in health and disease. However, the technique is expensive and often ...

Mapping biological networks in lung adenocarcinoma using transcriptomic analysis to identify prognostic biomarkers and therapeutic targets.

A single-cell atlas of brain aging epigenetics has mapped methylation, chromatin, and gene activity changes across 36 cell ...

New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...