How does APOE4 cause Alzheimer's? A new study identifies the Nell2 protein as the driver of neuron shrinkage and brain ...

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

Researchers have mapped how "histone bivalency" acts as a molecular clock for brain development. By holding genes in a poised state, this mechanism ensures neurons mature only after completing ...

Peer-reviewed publication validates the potential of Itay&Beyond's human CNS platform for advanced disease stratification, translational ...

A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...

The brain is the most complex organ in the human body. Different parts of the brain perform a variety of functions, all of ...

TalTech scientists in collaboration with researchers from Rockefeller University have described a mechanism that acts like a ...

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When ...

BOSTON, Mass. (July 15, 2024)—A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children’s Hospital has revealed that an immune protein impacts neuronal protein synthesis in ...

The brain is probably the least explored organ, much of which is due to the difficulty of studying it in situ rather than in slices under a microscope. Even growing small organoids out of neurons ...