Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

Leuven, 7 August 2024—The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU ...

The study builds on decades of research into dopaminergic neuron development and Parkinson's disease led by the late Prof. Ernest Arenas. His work laid important foundations for understanding how ...

Researchers have mapped how "histone bivalency" acts as a molecular clock for brain development. By holding genes in a poised state, this mechanism ensures neurons mature only after completing ...

Brain functions such as motivated behavior, reward learning and decision making are enabled by inhibitory projection neurons. Researchers now show that the protein MEIS2 plays an essential role in the ...

Study reveals how proteins direct nerve cell precursors to turn into specialized neurons. Brain development is a highly orchestrated process involving numerous parallel and sequential steps. Many of ...

ALS is a heterogeneous disease. While 10-15% of cases are linked to inherited mutations, nearly 85% are sporadic.

The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU Leuven Center for ...

Subscribe to our newsletter for the latest sci-tech news updates. The researchers also identified a second progenitor cell type that supports dopaminergic neuron development and survival. Dopaminergic ...

Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium ...