Once considered cellular junk, non-coding RNAs are emerging as key players in everything from brain development to cancer — ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

Long non-coding RNAs exist in the so-called "Wild West" (99%) of the human genome that is currently understudied. Not only does this finding have treatment implications for patients with ...

Image Caption: Technologies evolved related to the Human Genome Project. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on ...

Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize ...

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...

Researchers announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...

For decades, scientists have been puzzled by large portions of the human genome labeled as “junk” DNA, sequences that seemingly serve no purpose. Yet, recent studies suggest these cryptic sequences ...